Description
Mounjaro works by activating two key hormone receptors in the gut:
GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1).
These are incretin hormones, which naturally help regulate blood sugar levels in response to eating. Mounjaro mimics the effects of both GIP and GLP-1, enhancing their activity in the body. This dual-action mechanism helps:
• Release insulin when blood sugar is high
• Lower blood sugar levels
• To stop the liver from making and releasing too much sugar
• Slows passing of food through the stomach, which prolongs feelings of fullness
• Reduce appetite and food intake, supporting weight loss
By targeting both pathways, Mounjaro provides a more comprehensive effect on appetite control, glucose regulation, and weight management.
E-Meds Mounjaro Treatment Overview
Mounjaro is a once-weekly injection designed to support weight loss and blood sugar control. It is self-administered under the skin—typically in the abdomen, thigh, or upper arm—as per manufacturer guidelines. The injection site should be rotated after each dose. It can be taken with or without meals at any time of the day
Available Strengths of Mounjaro Pens
E-Meds supply Mounjaro as pre-filled, Kwikpen in the following strengths:
• 2.5 mg / 0.6 mL – 1pen containing 4 doses
• 5 mg / 0.6 mL – 1pen containing 4 doses
• 7.5 mg / 0.6 mL – 1pen containing 4 doses
• 10 mg / 0.6 mL – 1pen containing 4 doses
• 12.5 mg / 0.6 mL – 1pen containing 4 doses
• 15 mg / 0.6 mL – 1pen containing 4 doses
These pens are designed for easy, once-weekly self-injection and allow for stepwise dose increases based on individual treatment plans.
Treatment usually begins with a low starting dose of 2.5 mg per week for the first 4 weeks after the initial consultation with our healthcare professionals. After that, the dose may be gradually increased by 2.5 mg every 4 weeks, up to a maximum of 15 mg weekly, depending on individual response and tolerability.
The medication works by targeting hormones that influence appetite and digestion, helping people feel full sooner, stay satisfied longer, and experience fewer food cravings. As a result, it becomes easier to eat less and lose weight over time.
Understanding the Risks and Safety of Mounjaro
Mounjaro is effective for weight loss and blood sugar control, but like all medications, it can cause side effects. Here’s what you need to know to stay safe while taking them.
Common Side Effects
Many people taking Mounjaro experience mild to moderate stomach-related issues, especially when starting or titrating up their dose. The most common side effects include:
• Nausea
• Vomiting
• Diarrhoea
• Constipation
• Stomach pain
• Indigestion
• Burping
These side effects are usually temporary and go away over time. However, if they become severe, they could lead to dehydration, which may cause serious issues like kidney problems. Make sure to drink plenty of fluids and let your doctor know if you feel very unwell.
Some people may also experience:
• Mild hair loss
• Skin rashes
• Redness or irritation where the injection is given
These are generally not serious and go away with time.
Most Serious Side Effects (Less common)
Acute Pancreatitis
Although rare, some people taking GLP-1 medicines like Mounjaro may develop inflammation of the pancreas (called acute pancreatitis). This is a serious condition. Watch out for:
• Severe, ongoing pain in the stomach that moves to your back
• Nausea or vomiting that doesn’t go away
If you have these symptoms, seek medical help straight away. If pancreatitis is confirmed, the medicine will need to be stopped permanently.
Gallbladder Problems
Some people taking Mounjaro have developed gallbladder issues.
Inform your doctor right away if you notice any of the following symptoms:
• Pain in the upper right side of your stomach (abdomen)
• Fever
• Yellowing of your skin or eyes (this is called jaundice)
• Clay-coloured or pale stools
These could be signs of a gallbladder problem, such as gallstones or inflammation, and should seek medical attention.
Serious Allergic Reactions – When to Get Help
Stop using Mounjaro right away and seek emergency medical help if you experience any of the following:
• Swelling of your face, lips, tongue, or throat
• Trouble breathing or swallowing
• A severe rash or intense itching
• Fainting or feeling very dizzy
• A very fast heartbeat
These may be signs of a serious allergic reaction, which can be life-threatening if not treated quickly.
Pregnancy and Contraception
Mounjaro should not be taken during pregnancy or when planning to become pregnant, because we don’t yet know if they are safe for unborn babies.
If you’re planning a pregnancy:
• Stop Mounjaro (tirzepatide) at least 1 month before trying to get pregnant
If you’re using the pill:
Mounjaro may reduce the effectiveness of oral contraceptives, especially in people who are overweight. Use an additional or different form of birth control (like condoms, an IUD, or implant) for 4 weeks after starting Mounjaro and after every dose increase.
Breastfeeding
Do not take Mounjaro while breastfeeding, as it is unknown if they’re safe for babies. Always speak with a healthcare professional for advice.
Mental Health
There is no current evidence that GLP-1 medicines cause depression or suicidal thoughts.
If you do feel low or have any worrying thoughts, speak to someone immediately—a healthcare professional, friend, or mental health service.
Before Surgery or Operations
Tell your doctor or surgical team if you’re taking a GLP-1 medicine like Mounjaro. As Mounjaro slows down how quickly your stomach empties, this could increase the risk of complications under general anaesthesia (used during surgery). Your healthcare team might need to adjust your pre-surgery instructions.
Missed a Dose of Mounjaro? Here’s What to Do:
• If you remember within 4 days (96 hours):
Take the missed dose as soon as you remember.
• If more than 4 days have passed:
Skip the missed dose. Just take your next dose on your regular scheduled day.